A selection of the PROLIFICA team publications
Screen and treat intervention for chronic hepatitis B in West Africa (Gambia and Senegal)
Hepatitis B Core-Related Antigen to Indicate High Viral Load: Systematic Review and Meta-Analysis of 10,397 Individual Participants. Clin Gastroenterol Hepatol. 2021 Jan;19(1):46-60.e8.
Prevalence of occult hepatitis B virus infection in adults: a systematic review and meta-analysis, The Lancet Gastroenterology & Hepatology, 2022.
Clinical utility of quantifying hepatitis B surface antigen in African patients with chronic hepatitis B. J Viral Hepat. 2021 Jul;28(7):1003-1010.
Prevalence and clinical significance of occult hepatitis B infection in The Gambia, West Africa. J Infect Dis. 2021
Acceptability and feasibility of a screen-and-treat programme for hepatitis B virus infection in The Gambia: the Prevention of Liver Fibrosis and Cancer in Africa (PROLIFICA) study. Lancet Global Health 2016
Hepatitis B virus (HBV) infection amongst children in Senegal: current prevalence and seroprotection level. Pan African Journal, 2019.
Hepatitis B testing and treatment in HIV patients in The Gambia-Compliance with international guidelines and clinical outcomes. Plos One 2017
Improving communication about viral hepatitis in Africa. Lancet ID 2017
Prevention of liver fibrosis and liver cancer linked to hepatitis B virus in Africa: the Prolifica study. Med Sci 2019
Prevention of HBV mother-to-child transmission in sub-Saharan Africa
Coverage and Timeliness of Birth Dose Vaccination in Sub-Saharan Africa: A Systematic Review and Meta-Analysis. Vaccines (Basel). 2020 Jun 11;8(2):301.
Coverage and Timeliness of Birth Dose Vaccination in Sub-Saharan Africa: A Systematic Review and Meta-Analysis Vaccines 2020
Mother to child transmission of hepatitis B: What more needs to be done to eliminate it around the world? J Viral Hep 2019
Mother-to-child transmission of hepatitis B in sub-Saharan Africa, Lancet Infect Dis. 2016
HBV: simplified diagnostic algorithms
Assay for Hepatitis B Core-related Antigen Identify Patients With High Viral Load: Systematic Review and Meta-analysis of Individual Participant Data. Clin Gastroenterol Hepatol . 2020
Hepatitis B core-related antigen (HBcrAg): an alternative to HBV DNA to assess treatment eligibility in Africa Clin Infect Dis 2019.
Development of a simple score based on HBeAg and ALT for selecting patients for HBV treatment in Africa. J Hepatol 2018
Performance of two simplified HBV treatment criteria (TREAT-B score and WHO guidelines) in Burkina Faso, West Africa. J Hepatol. 2019.
Validation of rapid point-of-care (POC) tests for detection of hepatitis B surface antigen in field and laboratory settings in the Gambia, Western Africa, J Clin Microbiol. 2015
HCV in Africa
Hepatitis C virus infection in people who inject drugs in Africa Lancet Infect Dis. 2020 Mar;20(3):282-283.
Hepatitis C virus infection in people who inject drugs in Africa. Lancet Infect Dis. 2020 Mar;20(3):283-284.
Scaling up HCV treatment in resource-limited countries. Nat Rev Gastroenterol Hepatol 2015.
High prevalence and poor linkage to care of transfusion-transmitted infections among blood donors in Dar-es-Salaam, Tanzania. J Viral hep 2019
Scaling up prevention and treatment towards the elimination of hepatitis C: a global mathematical model. Lancet 2019
Biomakers of cirrhosis and hepatocellular carcinoma
Hepatitis B virus preS2Δ38-55 variants: A newly identified risk factor for hepatocellular carcinoma. JHEP Rep. 2020 Jul 11;2(5):100144.
Battelfield against hepatitis B infection and HCC in Africa, J Heptol. 2017
Health economic analysis and global perspective
Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission. Lancet Gastro Hepatol 2019