Although high alcohol consumption is one of the main causes of cirrhosis in Europe and North America, in many Asian and African countries hepatitis B virus is the most common cause of chronic liver disease and mainly affects young people.
PROLIFICA hepatitis B research activities currently focus on four main objectives:
- Demonstrate that screening for chronic hepatitis B and treatment of the infection is an effective way of reducing the burden of liver cancer in Africa
- Develop simplified diagnostic and monitoring algorithms in order to scale-up screen-and-treat interventions and eventually eliminate HBV in Africa
- Assess the rate and risk factors of liver disease progression in the African environment
- Identify strategies adapted to the African setting to prevent early transmission of the virus
Source: WHO, 2017